S.T. Charette
S.T. Charette has been trained as a research scientist in the fields of genetics and immunology. Specifically, in the areas of cancer and diabetes. He is currently earning a Pharm.D. at ACPHS.
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- 5/23/2006
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Masters in Immunology and a Ph.D. in Biomedical Genetics; Currently working towards a Pharm.D. at AlbanyFavorites
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Displaying Results 1 - 46 (of 46) for All Content
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Fruits for Diabetics: Why It's a Great IdeaFruits satisfy the sweet-tooth and are a great source of nutrients for diabetic patients. This article describes both the rational for including fruits in a diabetics diet and provides several examples.
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The Link Between Sexually Transmitted Diseases and Erectile Dysfunction DrugsA link between drugs that treat erectile dysfunction and STD's has been suggested in the literature. However, this link may have more to do with poor lifestyle choices than any adverse drug reaction.
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B Vitamins After a Heart Attack: Will They Prevent the Next One?A study published in the journal JAMA assessed whether or not supplemention with folic acid and vitamin B12 is beneficial after a heart attack.
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Genetic Mutations Associated with Crohn's Disease May Need a Helping HandA study published in the journal Cell suggests that a viral trigger may be needed to bring about a Crohn's disease like state in mice with a genetic mutation commonly found in humans with the disease.
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Preventing Diabetic Retinopathy in Patients with Cardiovascular RiskA new study assessed the intensity of glycemic control, lipid management, and hypertension, in preventing diabetic retinopathy in patients at risk for cardiovascular disease.
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MiRNAs Regulating Other MiRNAs in Cancer MetastasisA new study published in the journal Cell suggests that certain miRNAs can globally down-regulate other miRNAs in the process of cancer metastasis.
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Preventing HIV Transmission from Mother to Child After BirthA new study assessed various methods of preventing mother to child transmission of HIV after birth.
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Adding a Fibrate to Statin Therapy in Type 2 DiabetesA new study published in the New England Journal of Medicine assessed the benefit of adding fenofibrate to statin therapy in type 2 diabetics to prevent cardiovascular events.
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Blood Pressure Control in Diabetics: How Much is Too Much?A new study published in the New England Journal of Medicine suggests that lowering blood pressure in diabetics at high risk for cardiovascular disease below the currently suggested levels may not be beneficial.
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Increasing Anti-Cancer Drug Efficacy with a Tumor- Penetrating PeptideA new study published in the journal Science characterized the effectiveness of a novel peptide in increasing the permeability of tumors to anti-cancer drugs.
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Tourette's Syndrome Linked to Faulty Histamine ProductionA new study published in The New England Journal of Medicine suggests that Tourrette's syndrome may be linked to defunct histamine signaling.
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Valsartan for Diabetes PreventionA new study published in The New England Journal of Medicine assessed the use of valsartan to prevent diabetes and cardiovascular events in patients with impaired glucose tolerance.
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The "No Hit" Model of Cancer DevelopmentA new study published in the journal Nature Genetics suggests that modestly decreasing the level of the tumor suppressor PTEN is sufficient to increase cancer development in mice.
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Regenerating Beta Cells in the Pancreas: Implications for Diabetes TherapyLoss of insulin secreting beta cells in the pancreas is a hallmark of diabetes. A new study suggests that alpha cells in the pancreas may convert into beta cells to compensate.
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The Link Between Environmental Health and Human HealthThe environment and human health are linked in both logical and obscure ways. The following article discusses such contrasting links in relation to infectious disease.
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Optimizing Crohn's Treatment: Hit It Hard or Be Conservative?A new study published in the New England Journal of Medicine assessed the efficiency and benefit of treating Crohn's disease patients with more potent therapies usually reserved for treatment failure.
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Targeting Mitochondria in Cardiac DiseaseA new study published in the journal Circulation assessed the role of mitochondrial dynamics in cardiac injury and its potential exploitation in therapy.
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A New Study Uncovers the Importance of Mitochondrial FusionAlthough mitochondrial fusion is known to occur, little is know about its physiological function. A new study published in Cell investigated the role of this phenomenon in developing muscle.
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Human Genetics May Regulate Meningitis SeverityA new study suggests that human genetics may play a role in the severity of bacterial meningitis.
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COSMOS: a Long-Term Trial Geared to Assess the Health Risks of Cell Phone UseCOSMOS: A new large, international, and long term study launched to assess the long term safety of cell phone usage.
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The Interplay Between Depression and InsomniaDepression has long been thought to be linked with insomnia. This article discusses evidence suggesting that insomnia may be causative for depression rather than the long held belief that it is a consequence.
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MiR-9: A Potential Therapeutic Target for Invasive Breast CancerA new study published in Nature Cell Biology suggests the micro RNA (miRNA) miR-9 regulates breast cancer metastasis, making it a potential therapeutic target for the future.
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Acne Treatment for HIVA new study published in The Journal of Infectious Diseases suggests that an established acne treatment may ultimately have a place in HIV therapy.
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Mouse Transcriptome Offers Hope to ALS PatientsA new study published in the journal Nature Genetics used temporal transcriptional profiling of the ALS mouse model to discover a novel therapeutic strategy.
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The Different Types of Alzheimer'sThere are two major forms of Alzheimer's disease, late-onset and familial early-onset. This article compares and contrasts these two different types of Alzheimer's.
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Delaying the Progression from Pre-diabetes to Type 2 Diabetes: What Patients Should KnowThe following article reviews current knowledge about the steps patients with pre-diabetes can take that may prevent the progression to type 2 diabetes.
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A New Hope for Fighting Multi-Drug Resistant Pseudomonas Aeruginosa Nosocomial InfectionsPseudomonas aeruginosa is an opportunistic pathogen that often causes hospital-acquired infections. Multidrug resistance is becoming more common with this bacteria and a novel study offers a new hope for treatment.
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Do Statins Cause Diabetes?A new study published in the journal The Lancet assessed data from numerous clinical trials to investigate the link between diabetes and statin use.
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SPC3649: Targeting the Liver to Combat Hepatitis-C VirusSPC3649 is a novel drug that targets a liver specific gene to inhibit the replication of the liver damaging hepatitis-C virus.
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Leukemia Therapy Offers Hope to Multiple Sclerosis PatientsClabridine is a drug often used to treat various types of leukemia. However, this drug may have a dual role in treating multiple sclerosis.
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Inflammation: Linking Obesity with Cancer RiskA new study published in the journal Cell studied the link between obesity and cancer development using a liver cancer mouse model.
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How to Prevent Thinning HairThe following article reviews the current literature on what leads to thinning of the hair and how this information may be used, in some instances, to prevent or alleviate it.
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Tracking the Household Transmission of H1N1 (Swine Flu) Influenza VirusH1N1 (swine flu) influenza virus has a different transmission pattern compared to seasonal flu. A recent study in the New England Journal of Medicine tracked the household spread of swine flu to look for individuals more susceptible than others.
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The Parkinson's Disease Susceptibility Gene PARK2 May Also Function as a Tumor SuppressorPARK2 is as gene that is associated with early-onset Parkinson's disease when mutated. However, recent work in Nature Genetics suggests this gene may also function as a tumor suppressor.
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Short Telomeres Are Heritable and Promote Premature Aging in MiceTelomeres are buffers that protect the integrity of chromosomes. Shortening of telomeres has been linked with aging and disease. A new study suggests that short telomeres can actually be inherited and promote a premature aging phenotype.
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Prevention of Multiple Operations in Crohn's Disease Patients Using Immunosuppressive DrugsA new study suggests that long-term treatment with immunosuppressive agents may prevent the rate of re-operation in Crohn's disease patients requiring an initial surgery.
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A New Hope for Alzheimer's Disease: A Focus on IGF SignalingA new study published in the journal Cell suggests that reducing insulin-like growth factor (IGF) signaling may elicit a protective role against Alzheimer's disease.
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Niacin Added to Statin Therapy Improves Cardiovascular Outcomes Compared to EzetimibeA new study suggests that the addition of niacin to statin therapy improves atherosclerotic plaques and reduces adverse cardiovascular events better than augmentation with ezetimibe.
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A New Study Links Folic Acid and Vitamin-B12 to Increased Cancer RiskA new study in the journal JAMA suggests that folic acid and vitamin-B12 supplementation may increase the risk of cancer development. Although the data presented is alarming, its significance in regards to public safety in the United States is unclear.
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Nicotine Vaccines: The Future of Smoking CessationSmoking is a modifiable risk factor for multiple diseases and contributes to approximately 443,000 annual deaths in the United Sates. Nicotine vaccine technology offers a novel alternative for those with difficulties quitting.
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Concerns Over the Swine Flu (H1N1) VaccinePublic concerns over the safety of the swine flu (H1N1) vaccine are based on the both its rapid development and the presence of thimerosal in some formulations. However, the swine flu (H1N1) vaccine has the same safety profile as the seasonal flu vaccine.
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The Biologic Stelara (Ustekinumab): Recently Approved for Plaque Psoriasis Therapy in the USPlaque psoriasis affects a significant portion of the global population. Stelara (Ustekinumab) is a novel biologic recently approved to treat moderate to severe manifestations of this disease.
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Targeting Host Cell Genes for HIV TreatmentMost therapies for HIV target viral genes. This may lead to the selection of treatment resistant virus over time. A novel approach to HIV therapy is to target host cell genes, as these genes do not mutate rapidly and may reduce resistance.
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Recommendations for the Seasonal and H1N1 (Swine Flu) Influenza Virus VaccinesA common question that arises during the flu season every year, and especially this flu season is: do I need to receive the flu vaccine? The seasonal influenza and H1N1 (swine flu) vaccines each have specific usage recommendations.
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Was the 1918 Influenza Pandemic Caused by an Avian Flu Virus?Recently, the virus responsible for the 1918 influenza pandemic was re-synthesized . The virus was characterized in mice and the genomic sequence was aligned with other known influenza viruses, yielding very interesting results. -
A Novel Micro-RNA (miRNA) Regulated Transgene Expression System: Implications for Gene TherapyGene therapy is used to correct defective genes involved in disease. An obstacle however, is the inactivation gene products by the immune system. A recent article in Nature Medicine describes a novel system to overcome this hurdle.